The NCCC is a federally funded HIV/AIDS education service based in the UCSF/SFGH Department of Family and Community Medicine. The NCCC encompasses two important consultation programs: the National HIV/Telephone Consultation Service (Warmline) and the National Clinicians' Post-Exposure Prophylaxis Hotline (PEPline).

The Warmline addresses clinicians’ questions about HIV/AIDS, including antiretroviral therapy, clinical manifestations, and laboratory evaluation.

The PEPline provides 24-hour consultation for questions about occupational exposures to HIV and other blood-borne pathogens (e.g., needlesticks, splashes).

The Warmline and PEPline are staffed by UCSF faculty members, many of whom are graduates of the residency program.