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SFGH and Translational
Research
In September 2003, National Institutes of Health director Elias A.
Zerhouni unveiled a Roadmap Initiative that could transform the way NIH
funds research. To formulate the roadmap, Zerhouni organized meetings with
more than 300 biomedical experts over the course of 14 months, brainstorming
about clearing roadblocks to research that no single NIH institute could
overcome. Many of the recommendations in the NIH roadmap follow from the
Institute of Medicine’s report Enhancing the Vitality of the National
Institutes of Health: Organizational Change to Meet New Challenges. In response
to this report, NIH created an initiative that embraced the promotion of
translational research.
Translational research has two definitions. In the first, discoveries made
in the basic sciences, from molecular biology to physics, are translated
into improvements in clinical practice. The interaction of basic scientists
and clinician investigators bridges the gap from “bench to bedside”.
In the second, discoveries made by clinical investigators are translated
into community practice. There is active involvement in both forms of translational
research at SFGH.
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