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Results
at UCSF
So
far, the UCSF team has transplanted islet cells
into four Type 1 diabetes patients, ranging
in age form 25-48. Two of them had to have second
transplants; all four, however, have been able
to stop taking external insulin, because their
blood sugar levels have stabilized.
Tha success rate mirrors that
of other islet transplant centers across the
country.According to 2005 report by the Collaborative
Islet Transplant Registry (part of the National
Institute of Diabetes and Digestive and Kidney
Diseases), of the 138 patients who had received
islet transplants at 19 different centers, |
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40 patients received one islet cell infusion,
69 received two, 28 received three, and one
received four.
Six months after the patients' final infusions,
67 percent no longer needed insulin. One year
after the final infusion, 58 percent weren’t
using insulin. Those who were using insulin
needed, 69 percent less than they had before
the procedure. The study also found that episodes
of dangerously low blood glucose, or hypoglycemia,
were greatly reduced in patients who had undergone
the transplant.
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